Paradoxically Augmented Anti-Tumorigenic Action of Proton Pump Inhibitor and Gastrin in APCMin/+ Intestinal Polyposis Model1

Though long-term administration of proton pump inhibitor (PPI) imposed the risk of gastrointestinal track tumorigenesis by accompanied hypergastrinemia, no overt increases of colon cancer risk were witnessed after a long-term cohort study. Our recent investigation revealed that PPI prevented coliti...

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Bibliographic Details
Main Authors: Young-Min Han, Ki Baik Hahm, Jong-Min Park, Sung Pyo Hong, Eun-Hee Kim
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558614800079