Asialoglycoprotein receptor targeted delivery of doxorubicin nanoparticles for hepatocellular carcinoma

Asialoglycoprotein receptor targeted delivery of doxorubicin nanoparticles for hepatocellular carcinoma

We report asialoglycoprotein receptor (ASGPR)-targeted doxorubicin hydrochloride (Dox) nanoparticles (NPs) for hepatocellular carcinoma (HCC). Polyethylene sebacate (PES)-Gantrez® AN 119 Dox NPs of average size 220 nm with PDI < 0.62 and ∼20% Dox loading were prepared by modified nanoprecipitatio...

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Bibliographic Details
Main Authors: Sandhya Pranatharthiharan, Mitesh D. Patel, Vinod C. Malshe, Vaishali Pujari, Ajit Gorakshakar, Manisha Madkaikar, Kanjaksha Ghosh, Padma V. Devarajan
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Drug Delivery
Subjects:
pullulan
arabinogalactan
doxorubicin hydrochloride
asialoglycoprotein receptor
plc/prf/5 liver tumor
hepatocellular carcinoma
Online Access:http://dx.doi.org/10.1080/10717544.2016.1225856

Internet

http://dx.doi.org/10.1080/10717544.2016.1225856

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