A novel side effect of mitogen-activated protein kinase inhibitor cobimetinib: Acute corneal decompensation
A 38-year-old man with a diagnosis of BRAF-mutated metastatic melanoma was referred to our clinic. He had been under treatment with 60-mg oral cobimetinib daily for 21 days/7 day off in combination with 960 mg vemurafenib twice daily. The patient had symptoms of blurred vision and photophobia in his...
Main Authors: | Mahmut Asfuroglu, Yonca Asfuroğlu |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2019-01-01
|
Series: | Indian Journal of Ophthalmology |
Subjects: | |
Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=12;spage=2073;epage=2075;aulast=Asfuroglu |
Similar Items
-
Choroidal involvement in Rosai-Dorfman disease successfully treated with cobimetinib
by: Chiara Giuffrè, et al.
Published: (2020-01-01) -
Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF-mutated melanoma treated in the randomized coBRIM study
by: Luis de la Cruz-Merino, et al.
Published: (2017-06-01) -
Early Exanthema Upon Vemurafenib Plus Cobimetinib Is Associated With a Favorable Treatment Outcome in Metastatic Melanoma: A Retrospective Multicenter DeCOG Study
by: Katharina C. Kähler, et al.
Published: (2021-05-01) -
MEK inhibitors and their potential in the treatment of advanced melanoma: the advantages of combination therapy
by: Tran KA, et al.
Published: (2015-12-01) -
Panniculitis Associated with MEK Inhibitor Therapy: An Uncommon Adverse Effect
by: Miruna Negulescu, et al.
Published: (2017-03-01)