A novel side effect of mitogen-activated protein kinase inhibitor cobimetinib: Acute corneal decompensation

A 38-year-old man with a diagnosis of BRAF-mutated metastatic melanoma was referred to our clinic. He had been under treatment with 60-mg oral cobimetinib daily for 21 days/7 day off in combination with 960 mg vemurafenib twice daily. The patient had symptoms of blurred vision and photophobia in his...

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Bibliographic Details
Main Authors: Mahmut Asfuroglu, Yonca Asfuroğlu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=12;spage=2073;epage=2075;aulast=Asfuroglu