Nuclear translocation of the cytoplasmic domain of HB-EGF induces gastric cancer invasion

Nuclear translocation of the cytoplasmic domain of HB-EGF induces gastric cancer invasion

<p>Abstract</p> <p>Background</p> <p>Membrane-anchored heparin-binding epidermal growth factor-like growth factor (proHB-EGF) yields soluble HB-EGF, which is an epidermal growth factor receptor (EGFR) ligand, and a carboxy-terminal fragment of HB-EGF (HB-EGF-CTF) after...

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Bibliographic Details
Main Authors: Shimura Takaya, Yoshida Michihiro, Fukuda Shinji, Ebi Masahide, Hirata Yoshikazu, Mizoshita Tsutomu, Tanida Satoshi, Kataoka Hiromi, Kamiya Takeshi, Higashiyama Shigeki, Joh Takashi
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Cancer
Subjects:
EGFR
Gastric cancer
HB-EGF
Cancer invasion
Online Access:http://www.biomedcentral.com/1471-2407/12/205

Internet

http://www.biomedcentral.com/1471-2407/12/205

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