Stress-induced formation of cell wall-deficient cells in filamentous actinomycetes
Bacteria can be forced to grow without cell wall if cell wall synthesis is inhibited. Here Ramijan et al. show that, in filamentous actinomycetes, hyperosmotic stress induces formation of wall-deficient cells that can switch to normal mycelial growth, or mutate and proliferate indefinitely as wall-l...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2018-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-07560-9 |
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doaj-bfc3b934c7a14978b418423da1af76bd |
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Article |
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doaj-bfc3b934c7a14978b418423da1af76bd2021-05-11T10:04:33ZengNature Publishing GroupNature Communications2041-17232018-12-019111310.1038/s41467-018-07560-9Stress-induced formation of cell wall-deficient cells in filamentous actinomycetesKarina Ramijan0Eveline Ultee1Joost Willemse2Zheren Zhang3Joeri A. J. Wondergem4Anne van der Meij5Doris Heinrich6Ariane Briegel7Gilles P. van Wezel8Dennis Claessen9Molecular Biotechnology, Institute of Biology, Leiden UniversityMolecular Biotechnology, Institute of Biology, Leiden UniversityMolecular Biotechnology, Institute of Biology, Leiden UniversityMolecular Biotechnology, Institute of Biology, Leiden UniversityBiological and Soft Matter Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden UniversityMolecular Biotechnology, Institute of Biology, Leiden UniversityBiological and Soft Matter Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden UniversityMolecular Biotechnology, Institute of Biology, Leiden UniversityMolecular Biotechnology, Institute of Biology, Leiden UniversityMolecular Biotechnology, Institute of Biology, Leiden UniversityBacteria can be forced to grow without cell wall if cell wall synthesis is inhibited. Here Ramijan et al. show that, in filamentous actinomycetes, hyperosmotic stress induces formation of wall-deficient cells that can switch to normal mycelial growth, or mutate and proliferate indefinitely as wall-less forms.https://doi.org/10.1038/s41467-018-07560-9 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Karina Ramijan Eveline Ultee Joost Willemse Zheren Zhang Joeri A. J. Wondergem Anne van der Meij Doris Heinrich Ariane Briegel Gilles P. van Wezel Dennis Claessen |
| spellingShingle |
Karina Ramijan Eveline Ultee Joost Willemse Zheren Zhang Joeri A. J. Wondergem Anne van der Meij Doris Heinrich Ariane Briegel Gilles P. van Wezel Dennis Claessen Stress-induced formation of cell wall-deficient cells in filamentous actinomycetes Nature Communications |
| author_facet |
Karina Ramijan Eveline Ultee Joost Willemse Zheren Zhang Joeri A. J. Wondergem Anne van der Meij Doris Heinrich Ariane Briegel Gilles P. van Wezel Dennis Claessen |
| author_sort |
Karina Ramijan |
| title |
Stress-induced formation of cell wall-deficient cells in filamentous actinomycetes |
| title_short |
Stress-induced formation of cell wall-deficient cells in filamentous actinomycetes |
| title_full |
Stress-induced formation of cell wall-deficient cells in filamentous actinomycetes |
| title_fullStr |
Stress-induced formation of cell wall-deficient cells in filamentous actinomycetes |
| title_full_unstemmed |
Stress-induced formation of cell wall-deficient cells in filamentous actinomycetes |
| title_sort |
stress-induced formation of cell wall-deficient cells in filamentous actinomycetes |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2018-12-01 |
| description |
Bacteria can be forced to grow without cell wall if cell wall synthesis is inhibited. Here Ramijan et al. show that, in filamentous actinomycetes, hyperosmotic stress induces formation of wall-deficient cells that can switch to normal mycelial growth, or mutate and proliferate indefinitely as wall-less forms. |
| url |
https://doi.org/10.1038/s41467-018-07560-9 |
| work_keys_str_mv |
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| _version_ |
1721448764939436032 |