Burn-induced heterotopic ossification from incidence to therapy: key signaling pathways underlying ectopic bone formation

Abstract Burn injury is one of the potential causes of heterotopic ossification (HO), which is a rare but debilitating condition. The incidence ranges from 3.5 to 5.6 depending on body area. Burns that cover a larger percentage of the total body surface area (TBSA), require skin graft surgeries, or...

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Bibliographic Details
Main Authors: Xianglin Hu, Zhengwang Sun, Fengfeng Li, Chaoyin Jiang, Wangjun Yan, Yangbai Sun
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:https://doi.org/10.1186/s11658-021-00277-6