A novel in vivo model of puncture-induced iris neovascularization.

To assess iris neovascularization by uveal puncture of the mouse eye and determine the role of angiogenic factors during iris neovascularization.Uveal punctures were performed on BalbC mouse eyes to induce iris angiogenesis. VEGF-blockage was used as an anti-angiogenic treatment, while normoxia- and...

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Bibliographic Details
Main Authors: Ophélie Beaujean, Filippo Locri, Monica Aronsson, Anders Kvanta, Helder André
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5489193?pdf=render