An Investigation into Antibacterial Activity of Fluoroquinolone-Derived Compounds on Two Gram-Negative Bacteria; Escherichia coli and Pseudomonas aeruginosa

Introduction: Quinolones are known as a class of antibiotics inhibiting two central enzymes involved in DNA replication and transcription i.e., DNA gyrase and topoisomerase IV. Among them, fluoroquinolones can be developed via substituting fluorine atoms at the sixth position of core quinolone struc...

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Bibliographic Details
Main Authors: Shokrollah Assar, Ali Darehkordi, Mohammad Moradi, Mahmood Sheikh Fathollahi, Soudeh Khanamani Falahati-Pour, Gholamhossein Hassanshahi
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2019-09-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/13117/41883_CE[Ra1]_F(KM)_PF1(AG_KM)_PFA(SHU)_PB(AG_KM)_PN(SL).pdf