Separately or combined, LukG/LukH is functionally unique compared to other staphylococcal bicomponent leukotoxins.

Staphylococcus aureus is a major human pathogen that elaborates several exotoxins. Among these are the bicomponent leukotoxins (BCLs), which include γ-hemolysin, Panton-Valentine leukocidin (PVL), and LukDE. The toxin components are classified as either F or S proteins, which are secreted individual...

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Bibliographic Details
Main Authors: Machi Yanai, Miguel A Rocha, Anthony Z Matolek, Archana Chintalacharuvu, Yasuhiko Taira, Koteswara Chintalacharuvu, David O Beenhouwer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3930693?pdf=render