Histone Deacetylase Inhibitors in Cell Pluripotency, Differentiation, and Reprogramming
Histone deacetylase inhibitors (HDACi) are small molecules that have important and pleiotropic effects on cell homeostasis. Under distinct developmental conditions, they can promote either self-renewal or differentiation of embryonic stem cells. In addition, they can promote directed differentiation...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2012-01-01
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Series: | Stem Cells International |
Online Access: | http://dx.doi.org/10.1155/2012/184154 |