Histone Deacetylase Inhibitors in Cell Pluripotency, Differentiation, and Reprogramming

Histone deacetylase inhibitors (HDACi) are small molecules that have important and pleiotropic effects on cell homeostasis. Under distinct developmental conditions, they can promote either self-renewal or differentiation of embryonic stem cells. In addition, they can promote directed differentiation...

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Bibliographic Details
Main Authors: Androniki Kretsovali, Christiana Hadjimichael, Nikolaos Charmpilas
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2012/184154