Graph regularized L 2,1-nonnegative matrix factorization for miRNA-disease association prediction

Abstract Background The aberrant expression of microRNAs is closely connected to the occurrence and development of a great deal of human diseases. To study human diseases, numerous effective computational models that are valuable and meaningful have been presented by researchers. Results Here, we pr...

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Bibliographic Details
Main Authors: Zhen Gao, Yu-Tian Wang, Qing-Wen Wu, Jian-Cheng Ni, Chun-Hou Zheng
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-3409-x