Association of CHRNA5-A3-B4 variation with esophageal squamous cell carcinoma risk and smoking behaviors in a Chinese population.

BACKGROUND:CHRNA5-A3-B4, the gene cluster encoding nicotinic acetylcholine receptor subunits, is associated with lung cancer risk and smoking behaviors in people of European descent. Because cigarette smoking is also a major risk factor for esophageal squamous cell carcinoma (ESCC), we investigated...

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Bibliographic Details
Main Authors: Yang Wang, Haijian Wu, Qiji Liu, Cuihong Wang, Lei Fu, Han Wang, Wenjie Zhu, Weijiang Fu, Yajuan Lv, Shikun Wang, Likuan Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3699625?pdf=render