The correlation of paraoxonase (PON1) activity with lipid and lipoprotein levels differs with vascular disease status

Paraoxonase (PON1) is an HDL-associated enzyme. Low PON1 activity predicts vascular disease status and is a more reliable predictor of vascular disease than are functional PON1 genotypes. There is evidence that the relationship of PON1 to vascular disease is, in part, due to its antioxidant activity...

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Bibliographic Details
Main Authors: Laura S. Rozek, Thomas S. Hatsukami, Rebecca J. Richter, Jane Ranchalis, Karen Nakayama, Laura A. McKinstry, David A. Gortner, Edward Boyko, Gerard D. Schellenberg, Clement E. Furlong, Gail P. Jarvik
Format: Article
Language:English
Published: Elsevier 2005-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520329357