In vitro differentiation of cGMP-grade retinal pigmented epithelium from human embryonic stem cells

Abstract Background The World Health Organization (WHO) estimates that the number of individuals who lose their vision due to retinal degeneration is expected to reach 6 million annually in 2020. The retinal degenerative diseases affect the macula, which is responsible for central and detailed visio...

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Bibliographic Details
Main Authors: Fernando H. Lojudice, Rodrigo A. Brant Fernandes, Francesco Innocenti, Carlos E. Franciozi, Priscila Cristovam, Maurício Maia, Mari C. Sogayar, Rubens Belfort
Format: Article
Language:English
Published: BMC 2019-10-01
Series:International Journal of Retina and Vitreous
Online Access:http://link.springer.com/article/10.1186/s40942-019-0194-7