Characterization of New TRPM8 Modulators in Pain Perception

Characterization of New TRPM8 Modulators in Pain Perception

Background: Transient Receptor Potential Melastatin-8 (TRPM8) is a non-selective cation channel activated by cold temperature and by cooling agents. Several studies have proved that this channel is involved in pain perception. Although some studies indicate that TRPM8 inhibition is necessary to redu...

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Bibliographic Details
Main Authors: Carmen De Caro, Claudia Cristiano, Carmen Avagliano, Alessia Bertamino, Carmine Ostacolo, Pietro Campiglia, Isabel Gomez-Monterrey, Giovanna La Rana, Oreste Gualillo, Antonio Calignano, Roberto Russo
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
trpm8
orofacial pain
neuropathic pain
local application
systemic administration
Online Access:https://www.mdpi.com/1422-0067/20/22/5544

Internet

https://www.mdpi.com/1422-0067/20/22/5544

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