First Synthesis of a Natural Neopterin Glycoside: 3'-O-(β-D-Glucopyranosyluronic acid)neopterin

First Synthesis of a Natural Neopterin Glycoside: 3'-O-(β-D-Glucopyranosyluronic acid)neopterin

1',2'-Di-O-acetyl-N2-(N,N-dimethylaminomethylene)-3-[2-(4-nitrophenyl)ethyl]neopterin (1) was prepared from neopterin in 5 steps. Glycosylation of 1 with methyl 2,3,4-tri-O-benzoyl-α-D-glucopyranosyluronate bromide in the presence of silver triflate and tetramethylurea afforded the corresp...

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Bibliographic Details
Main Authors: Hanaya Tadashi, Hattori Takafumi, Takayama Daisuke, Yamamoto Hiroshi
Format: Article
Language:English
Published: De Gruyter 2010-02-01
Series:Pteridines
Subjects:
neopterin glycoside
d-glucronic acid
glycosylation
protecting groups
Online Access:https://doi.org/10.1515/pteridines.2010.21.1.79

Internet

https://doi.org/10.1515/pteridines.2010.21.1.79

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