The Soluble Form of Toll-Like Receptor 2 Is Elevated in Serum of Multiple Sclerosis Patients: A Novel Potential Disease Biomarker

The Soluble Form of Toll-Like Receptor 2 Is Elevated in Serum of Multiple Sclerosis Patients: A Novel Potential Disease Biomarker

Multiple sclerosis (MS) is an immune-mediated inflammatory demyelinating disease of the central nervous system. It was previously shown that toll-like receptor (TLR)-2 signaling plays a key role in the murine experimental autoimmune encephalomyelitis (EAE) model of MS, and that TLR2-stimulation of r...

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Bibliographic Details
Main Authors: Md Jakir Hossain, Elena Morandi, Radu Tanasescu, Nanci Frakich, Marzia Caldano, David Onion, Tola A. Faraj, Clett Erridge, Bruno Gran
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Immunology
Subjects:
toll-like receptor 2
soluble TLR2
multiple sclerosis
urinary tract infection
biomarker
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00457/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00457/full

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