The RNA sensor MDA5 detects SARS-CoV-2 infection

The RNA sensor MDA5 detects SARS-CoV-2 infection

Abstract Human cells respond to infection by SARS-CoV-2, the virus that causes COVID-19, by producing cytokines including type I and III interferons (IFNs) and proinflammatory factors such as IL6 and TNF. IFNs can limit SARS-CoV-2 replication but cytokine imbalance contributes to severe COVID-19. We...

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Bibliographic Details
Main Authors: Natalia G. Sampaio, Lise Chauveau, Jonny Hertzog, Anne Bridgeman, Gerissa Fowler, Jurgen P. Moonen, Maeva Dupont, Rebecca A. Russell, Marko Noerenberg, Jan Rehwinkel
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92940-3

Internet

https://doi.org/10.1038/s41598-021-92940-3

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