Peripheral T-lymphocytes express WNT7A and its restoration in leukemia-derived lymphoblasts inhibits cell proliferation

Peripheral T-lymphocytes express WNT7A and its restoration in leukemia-derived lymphoblasts inhibits cell proliferation

<p>Abstract</p> <p>Background</p> <p>WNT7a, a member of the Wnt ligand family implicated in several developmental processes, has also been reported to be dysregulated in some types of tumors; however, its function and implication in oncogenesis is poorly understood. Mor...

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Bibliographic Details
Main Authors: Ochoa-Hernández Alejandra B, Ramos-Solano Moisés, Meza-Canales Ivan D, García-Castro Beatriz, Rosales-Reynoso Mónica A, Rosales-Aviña Judith A, Barrera-Chairez Esperanza, Ortíz-Lazareno Pablo C, Hernández-Flores Georgina, Bravo-Cuellar Alejandro, Jave-Suarez Luis F, Barros-Núñez Patricio, Aguilar-Lemarroy Adriana
Format: Article
Language:English
Published: BMC 2012-02-01
Series:BMC Cancer
Subjects:
WNT7A
Wnt signaling
Leukemia
Anti-proliferative
Non-canonical pathway
Online Access:http://www.biomedcentral.com/1471-2407/12/60

Internet

http://www.biomedcentral.com/1471-2407/12/60

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