Phenotypic and functional properties of Helios+ regulatory T cells.

Phenotypic and functional properties of Helios+ regulatory T cells.

Helios, an Ikaros family transcription factor, is preferentially expressed at the mRNA and protein level in regulatory T cells. Helios expression previously appeared to be restricted to thymic-derived Treg. Consistent with recent data, we show here that Helios expression is inducible in vitro under...

Full description

Bibliographic Details
Main Authors: Daniel J Zabransky, Christopher J Nirschl, Nicholas M Durham, Ben V Park, Christina M Ceccato, Tullia C Bruno, Ada J Tam, Derese Getnet, Charles G Drake
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3316700?pdf=render

Internet

http://europepmc.org/articles/PMC3316700?pdf=render

Similar Items