Histone Deacetylase-Mediated Müller Glia Reprogramming through Her4.1-Lin28a Axis Is Essential for Retina Regeneration in Zebrafish

Histone Deacetylase-Mediated Müller Glia Reprogramming through Her4.1-Lin28a Axis Is Essential for Retina Regeneration in Zebrafish

Summary: Histone deacetylases (Hdacs) play significant roles in cellular homeostasis and tissue differentiation. Hdacs are well characterized in various systems for their physiological and epigenetic relevance. However, their significance during retina regeneration remains unclear. Here we show that...

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Bibliographic Details
Main Authors: Soumitra Mitra, Poonam Sharma, Simran Kaur, Mohammad Anwar Khursheed, Shivangi Gupta, Riya Ahuja, Akshai J. Kurup, Mansi Chaudhary, Rajesh Ramachandran
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218301202

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http://www.sciencedirect.com/science/article/pii/S2589004218301202

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