Gene Signature of High White Blood Cell Count in B-Precursor Acute Lymphoblastic Leukemia.

In this study we sought to identify genetic factors associated with the presenting white blood cell (WBC) count in B-precursor acute lymphoblastic leukemia (BP-ALL). Using ETV6-RUNX1-positive BP-ALL patient samples, a homogeneous subtype, we identified 16 differentially expressed genes based on the...

Full description

Bibliographic Details
Main Authors: Holly Edwards, Mara Rubenstein, Alan A Dombkowski, J Timothy Caldwell, Roland Chu, Ana C Xavier, Ryan Thummel, Melody Neely, Larry H Matherly, Yubin Ge, Jeffrey W Taub
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0161539