Heterochromatin assembly and transcriptome repression by Set1 in coordination with a class II histone deacetylase

Heterochromatin assembly and transcriptome repression by Set1 in coordination with a class II histone deacetylase

Histone modifiers play essential roles in controlling transcription and organizing eukaryotic genomes into functional domains. Here, we show that Set1, the catalytic subunit of the highly conserved Set1C/COMPASS complex responsible for histone H3K4 methylation (H3K4me), behaves as a repressor of the...

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Bibliographic Details
Main Authors: David R Lorenz, Lauren F Meyer, Patrick J R Grady, Michelle M Meyer, Hugh P Cam
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-12-01
Series:eLife
Subjects:
set1
heterochromatin
transcriptome
atf1
HDAC
chromatin
Online Access:https://elifesciences.org/articles/04506

Internet

https://elifesciences.org/articles/04506

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