Pax6 regulates gene expression in the vertebrate lens through miR-204.

During development, tissue-specific transcription factors regulate both protein-coding and non-coding genes to control differentiation. Recent studies have established a dual role for the transcription factor Pax6 as both an activator and repressor of gene expression in the eye, central nervous syst...

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Main Authors: Ohad Shaham, Karen Gueta, Eyal Mor, Pazit Oren-Giladi, Dina Grinberg, Qing Xie, Ales Cvekl, Noam Shomron, Noa Davis, Maya Keydar-Prizant, Shaul Raviv, Metsada Pasmanik-Chor, Rachel E Bell, Carmit Levy, Raffaella Avellino, Sandro Banfi, Ivan Conte, Ruth Ashery-Padan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3597499?pdf=render