Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain

Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain

Abstract We report a metabolomic analysis of Streptomyces sp. ID38640, a soil isolate that produces the bacterial RNA polymerase inhibitor pseudouridimycin. The analysis was performed on the wild type, on three newly constructed and seven previously reported mutant strains disabled in different gene...

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Bibliographic Details
Main Authors: Marianna Iorio, Sahar Davatgarbenam, Stefania Serina, Paolo Criscenzo, Mitja M. Zdouc, Matteo Simone, Sonia I. Maffioli, Richard H. Ebright, Stefano Donadio, Margherita Sosio
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84833-2

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https://doi.org/10.1038/s41598-021-84833-2

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