iDTi-CSsmoteB: Identification of Drug–Target Interaction Based on Drug Chemical Structure and Protein Sequence Using XGBoost With Over-Sampling Technique SMOTE

iDTi-CSsmoteB: Identification of Drug–Target Interaction Based on Drug Chemical Structure and Protein Sequence Using XGBoost With Over-Sampling Technique SMOTE

Identifying interaction between drug and protein is a crucial challenge in drug discovery, which can lead the researchers to develop novel drug compounds or new target proteins for the existing drugs. The determination of drug-target interactions (DTIs) is an extremely time-consuming, costly, and te...

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Bibliographic Details
Main Authors: S. M. Hasan Mahmud, Wenyu Chen, Hosney Jahan, Yongsheng Liu, Nasir Islam Sujan, Saeed Ahmed
Format: Article
Language:English
Published: IEEE 2019-01-01
Series:IEEE Access
Subjects:
AM-PseAAC
DP-PseAAC
drug-target interactions
molecular substructure fingerprint
over-sampling SMOTE
PSSM-Bigram
Online Access:https://ieeexplore.ieee.org/document/8686077/

Internet

https://ieeexplore.ieee.org/document/8686077/

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