Modeling the covariates effects on the hazard function by piecewise exponential artificial neural networks: an application to a controlled clinical trial on renal carcinoma

Abstract Background In exploring the time course of a disease to support or generate biological hypotheses, the shape of the hazard function provides relevant information. For long follow-ups the shape of hazard function may be complex, with the presence of multiple peaks. In this paper we present t...

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Bibliographic Details
Main Authors: Marco Fornili, Patrizia Boracchi, Federico Ambrogi, Elia Biganzoli
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2179-1