Phosphatidylcholine deficiency upregulates enzymes of triacylglycerol metabolism in CHO cells

Phosphatidylcholine deficiency upregulates enzymes of triacylglycerol metabolism in CHO cells

We studied the regulation of triacylglycerol (TAG) metabolism by phosphatidylcholine (PC) in CHO MT58 cells, which are deficient in PC synthesis because of a temperature-sensitive CTP:phosphocholine cytidylyltransferase. At the permissive growth temperature (34°C), these cells contained 49% less TAG...

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Bibliographic Details
Main Authors: J. Matías Caviglia, I. Nelva T. de Gómez Dumm, Rosalind A. Coleman, R. Ariel Igal
Format: Article
Language:English
Published: Elsevier 2004-08-01
Series:Journal of Lipid Research
Subjects:
phosphatidylcholine metabolism
triacylglycerol synthesis
lipolysis
diacylglycerol acyltransferase
lipase
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520313122

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http://www.sciencedirect.com/science/article/pii/S0022227520313122

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