A cross-species assessment of behavioral flexibility in compulsive disorders

Nabil Benzina et al. use a reversal learning task to examine behavioral flexibility in human and mouse models of obsessive compulsive disorder (OCD). They report that only subsets of human patients or OCD-like mice show deficits in behavioral flexibility, highlighting the diverse presentation of cog...

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Bibliographic Details
Main Authors: Nabil Benzina, Karim N’Diaye, Antoine Pelissolo, Luc Mallet, Eric Burguière
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-020-01611-y