Enhanced transduction of colonic cell lines <it>in vitro </it>and the inflamed colon in mice by viral vectors, derived from adeno-associated virus serotype 2, using virus-microbead conjugates bearing lectin

<p>Abstract</p> <p>Background</p> <p>Virus-mediated delivery of therapeutic transgenes to the inflamed colon holds a great potential to serve as an effective therapeutic strategy for inflammatory bowel disease, since local, long-term expression of the encoded therapeuti...

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Bibliographic Details
Main Authors: Sano Takeshi, Jerusalmi Alan, Farlow Samuel J
Format: Article
Language:English
Published: BMC 2007-11-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/7/83