Overcoming anticancer resistance by photodynamic therapy-related efflux pump deactivation and ultrasound-mediated improved drug delivery efficiency

Overcoming anticancer resistance by photodynamic therapy-related efflux pump deactivation and ultrasound-mediated improved drug delivery efficiency

Abstract One of the major obstacles to successful chemotherapy is multi-drug resistance (MDR). A multi-drug resistant cancerous cell abnormally overexpresses membrane transporters that pump anticancer drugs out of the cell, resulting in low anticancer drug delivery efficiency. To overcome the limita...

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Bibliographic Details
Main Authors: Doyeon Kim, Suhyun Park, Hongkeun Yoo, Suhyeon Park, Jeewon Kim, Kyuhee Yum, Kwangmeyung Kim, Hyuncheol Kim
Format: Article
Language:English
Published: SpringerOpen 2020-09-01
Series:Nano Convergence
Subjects:
Multidrug resistance
Nanomedicine
Ultrasound
Microbubble
Sonoporation
Efflux pump
Online Access:http://link.springer.com/article/10.1186/s40580-020-00241-8

Internet

http://link.springer.com/article/10.1186/s40580-020-00241-8

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