Modification of acetoacetyl-CoA reduction step in Ralstonia eutropha for biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from structurally unrelated compounds

Abstract Background Poly((R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate) [P(3HB-co-3HHx)] is a bacterial polyester with high biodegradability, even in marine environments. Ralstonia eutropha has been engineered for the biosynthesis of P(3HB-co-3HHx) from vegetable oils, but its production from stru...

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Bibliographic Details
Main Authors: Mengxiao Zhang, Shunsuke Kurita, Izumi Orita, Satoshi Nakamura, Toshiaki Fukui
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Microbial Cell Factories
Online Access:http://link.springer.com/article/10.1186/s12934-019-1197-7