Long-chain fatty acid activates hepatocytes through CD36 mediated oxidative stress

Long-chain fatty acid activates hepatocytes through CD36 mediated oxidative stress

Abstract Background Accumulating evidence suggests that activated hepatocytes are involved in the deposition of the excess extracellular matrix during liver fibrosis via the epithelial to mesenchymal transition. Lipid accumulation in hepatocytes are implicated in the pathogenesis of chronic liver in...

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Bibliographic Details
Main Authors: Jun Liu, Ping Yang, Guoqing Zuo, Song He, Wei Tan, Xiaoyu Zhang, Chunxiao Su, Lei Zhao, Li Wei, Yao Chen, Xiongzhong Ruan, Yaxi Chen
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Lipids in Health and Disease
Subjects:
CD36
LCFA
Hepatocyte activation
Oxidative stress
Online Access:http://link.springer.com/article/10.1186/s12944-018-0790-9

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http://link.springer.com/article/10.1186/s12944-018-0790-9

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