A Systematic Evaluation of Semispecific Peptide Search Parameter Enables Identification of Previously Undescribed N-Terminal Peptides and Conserved Proteolytic Processing in Cancer Cell Lines

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the most commonly used technique in explorative proteomic research. A variety of open-source tools for peptide-spectrum matching have become available. Most analyses of explorative MS data are performed using conventional settings,...

Full description

Bibliographic Details
Main Authors: Matthias Fahrner, Lucas Kook, Klemens Fröhlich, Martin L. Biniossek, Oliver Schilling
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Proteomes
Subjects:
Online Access:https://www.mdpi.com/2227-7382/9/2/26