Generating porcine chimeras using inner cell mass cells and parthenogenetic preimplantation embryos.

BACKGROUND: The development and validation of stem cell therapies using induced pluripotent stem (iPS) cells can be optimized through translational research using pigs as large animal models, because pigs have the closest characteristics to humans among non-primate animals. As the recent investigati...

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Bibliographic Details
Main Authors: Kazuaki Nakano, Masahito Watanabe, Hitomi Matsunari, Taisuke Matsuda, Kasumi Honda, Miki Maehara, Takahiro Kanai, Gota Hayashida, Mirina Kobayashi, Momoko Kuramoto, Yoshikazu Arai, Kazuhiro Umeyama, Shuh-Hei Fujishiro, Yoshihisa Mizukami, Masaki Nagaya, Yutaka Hanazono, Hiroshi Nagashima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3633951?pdf=render