SNHG1 promotes MPP+-induced cytotoxicity by regulating PTEN/AKT/mTOR signaling pathway in SH-SY5Y cells via sponging miR-153-3p

Abstract Background Long non-coding RNA small molecule RNA host gene 1 (SNHG1) was previously identified to be relevant with Parkinson’s disease (PD) pathogenesis. This work aims to further elucidate the regulatory networks of SNHG1 involved in PD. Methods 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridin...

Full description

Bibliographic Details
Main Authors: Jun Zhao, Lijiao Geng, Yong Chen, Chunfang Wu
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Biological Research
Subjects:
Online Access:https://doi.org/10.1186/s40659-019-0267-y