Prion Protein-Specific Antibodies-Development, Modes of Action and Therapeutics Application

Prion Protein-Specific Antibodies-Development, Modes of Action and Therapeutics Application

Prion diseases or Transmissible Spongiform Encephalopathies (TSEs) are lethal neurodegenerative disorders involving the misfolding of the host encoded cellular prion protein, PrPC. This physiological form of the protein is expressed throughout the body, and it reaches the highest levels in the centr...

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Bibliographic Details
Main Authors: Tihana Lenac Rovis, Giuseppe Legname
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Viruses
Subjects:
prion
PrP
antibody
recombinant antibody
immunotherapy
molecular mechanism
Online Access:http://www.mdpi.com/1999-4915/6/10/3719

Internet

http://www.mdpi.com/1999-4915/6/10/3719

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