Fas-Fas Ligand Interplay in the Periphery of Salivary Gland Carcinomas as a New Checkpoint Predictor for Disease Severity and Immunotherapy Response

Fas-Fas Ligand Interplay in the Periphery of Salivary Gland Carcinomas as a New Checkpoint Predictor for Disease Severity and Immunotherapy Response

Salivary gland carcinomas (SGCs) are extremely morphologically heterogeneous, and treatment options for this disease are limited. Immunotherapy with immune checkpoint inhibitors (ICIs) represents a revolutionary treatment approach. However, SGCs remain largely resistant to this therapy. An increasin...

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Bibliographic Details
Main Authors: Zuzana Strizova, Martin Kuchar, Linda Capkova, Martin Komarc, Jiri Skrivan, Jirina Bartunkova, Jan Plzak, Daniel Smrz
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
Fas
FasL
salivary gland carcinoma
tumor center
tumor periphery
Online Access:https://www.mdpi.com/2227-9059/9/4/402

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https://www.mdpi.com/2227-9059/9/4/402

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