Role of MCM2–7 protein phosphorylation in human cancer cells
Abstract A heterohexameric complex composed of minichromosome maintenance protein 2–7 (MCM2–7), which acts as a key replicative enzyme in eukaryotes, is crucial for initiating DNA synthesis only once per cell cycle. The MCM complex remains inactive through the G1 phase, until the S phase, when it is...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
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Series: | Cell & Bioscience |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13578-018-0242-2 |