Knockdown of NUDT21 inhibits proliferation and promotes apoptosis of human K562 leukemia cells through ERK pathway

Knockdown of NUDT21 inhibits proliferation and promotes apoptosis of human K562 leukemia cells through ERK pathway

Lan Zhang, Weihua Zhang Department of Haematology, First Hospital of Shanxi Medical University, Taiyuan 030001, China Background: NUDT21 is a mammalian precursor mRNA(pre-mRNA) 3’ end processing factor and plays an important role in the selection of poly(A) sites in 3’-untranslat...

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Bibliographic Details
Main Authors: Zhang L, Zhang WH
Format: Article
Language:English
Published: Dove Medical Press 2018-10-01
Series:Cancer Management and Research
Subjects:
NUDT21
MAPK/ERK
K562 cell line
leukemia
cell proliferation
cell apoptosis
Online Access:https://www.dovepress.com/knockdown-of-nudt21-inhibits-proliferation-and-promotes-apoptosis-of-h-peer-reviewed-article-CMAR

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https://www.dovepress.com/knockdown-of-nudt21-inhibits-proliferation-and-promotes-apoptosis-of-h-peer-reviewed-article-CMAR

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