Quantitative Proteomics Reveals the Beneficial Effects of Low Glucose on Neuronal Cell Survival in an in vitro Ischemic Penumbral Model

Quantitative Proteomics Reveals the Beneficial Effects of Low Glucose on Neuronal Cell Survival in an in vitro Ischemic Penumbral Model

Understanding proteomic changes in the ischemic penumbra are crucial to rescue those salvageable cells and reduce the damage of an ischemic stroke. Since the penumbra region is dynamic with heterogeneous cells/tissues, tissue sampling from animal models of stroke for the molecular study is a challen...

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Bibliographic Details
Main Authors: Hua Li, Farooqahmed S. Kittur, Chiu-Yueh Hung, P. Andy Li, Xinghong Ge, David C. Sane, Jiahua Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neuronal cells
ischemic penumbra
hypoxia
low glucose
proteomic analysis
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00272/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00272/full

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