Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections

Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections

Pauli et al. develop targeted volumetric dSTORM in order to image large hippocampal mossy fiber boutons (MFBs) in brain slices. They can identify synaptic targets of individual MFBs and measured size and density of Bassoon clusters within individual untruncated MFBs at nanoscopic resolution.

Bibliographic Details
Main Authors: Martin Pauli, Mila M. Paul, Sven Proppert, Achmed Mrestani, Marzieh Sharifi, Felix Repp, Lydia Kürzinger, Philip Kollmannsberger, Markus Sauer, Manfred Heckmann, Anna-Leena Sirén
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01939-z

Internet

https://doi.org/10.1038/s42003-021-01939-z

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