Size-exclusion chromatography can identify faster-associating protein complexes and evaluate design strategies

<p>Abstract</p> <p>Background</p> <p>We previously developed a set of rationally designed mutant MICA protein ligands for the NKG2D immunoreceptor in which MICA was mutated at residues that do not contact NKG2D. Some of these MICA mutants, predicted by RosettaDesign to...

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Bibliographic Details
Main Authors: Austin Chad R, VanSchoiack Andrew D, Swietlicka Monika A, Snyder W Kalani, Mayer Chad L, McFarland Benjamin J
Format: Article
Language:English
Published: BMC 2009-07-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/2/135