Host-species transferrin receptor 1 orthologs are cellular receptors for nonpathogenic new world clade B arenaviruses.

Host-species transferrin receptor 1 orthologs are cellular receptors for nonpathogenic new world clade B arenaviruses.

The ability of a New World (NW) clade B arenavirus to enter cells using human transferrin receptor 1 (TfR1) strictly correlates with its ability to cause hemorrhagic fever. Amapari (AMAV) and Tacaribe (TCRV), two nonpathogenic NW clade B arenaviruses that do not use human TfR1, are closely related t...

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Bibliographic Details
Main Authors: Jonathan Abraham, Jo Ann Kwong, César G Albariño, Jiajie G Lu, Sheli R Radoshitzky, Jorge Salazar-Bravo, Michael Farzan, Christina F Spiropoulou, Hyeryun Choe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-04-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19343214/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19343214/?tool=EBI

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