Senescent Hepatocytes in Decompensated Liver Show Reduced UPRMT and Its Key Player, CLPP, Attenuates Senescence In VitroSummary

Senescent Hepatocytes in Decompensated Liver Show Reduced UPRMT and Its Key Player, CLPP, Attenuates Senescence In VitroSummary

Background and Aims: Non-dividing hepatocytes in end-stage liver disease indicates permanent growth arrest similar to senescence. Identifying senescence in vivo is often challenging and mechanisms inhibiting senescence are poorly understood. In lower organisms mitochondrial unfolded protein response...

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Bibliographic Details
Main Authors: Bijoya Sen, Archana Rastogi, Rhisita Nath, Saggere M. Shasthry, Viniyendra Pamecha, Sonika Pandey, Kapuganti Jagadis Gupta, Shiv K. Sarin, Nirupma Trehanpati, Gayatri Ramakrishna
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X1930027X

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http://www.sciencedirect.com/science/article/pii/S2352345X1930027X

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