Stressed: The Unfolded Protein Response in T Cell Development, Activation, and Function
The unfolded protein response (UPR) is a highly conserved pathway that allows cells to respond to stress in the endoplasmic reticulum caused by an accumulation of misfolded and unfolded protein. This is of great importance to secretory cells because, in order for proteins to traffic from the endopla...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-04-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/7/1792 |