Design and selection of a camelid single-chain antibody yeast two-hybrid library produced de novo for the cap protein of porcine circovirus type 2 (PCV2).

Nanobodies (or variable domain of the heavy chain of the heavy-chain antibodies, VHHs) are single-domain antigen-binding fragments derived from camelid heavy chain antibodies. Their comparatively small size, monomeric behavior, high stability, high solubility, and ability to bind epitopes inaccessib...

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Bibliographic Details
Main Authors: Xiangjing Fu, Xiaolong Gao, Shengfang He, Di Huang, Peng Zhang, Xinglong Wang, Shuxia Zhang, Ruyi Dang, Shuanghui Yin, Enqi Du, Zengqi Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585807?pdf=render