Acacia hydaspica R. Parker prevents doxorubicin-induced cardiac injury by attenuation of oxidative stress and structural Cardiomyocyte alterations in rats

Acacia hydaspica R. Parker prevents doxorubicin-induced cardiac injury by attenuation of oxidative stress and structural Cardiomyocyte alterations in rats

Abstract Background The use of doxorubicin (DOX) an anthracycline antineoplastic agent is withdrawn due to its cardio-toxic side effects. Oxidative stress has been recognized as the primary cause of DOX induced cardiotoxicity. We have investigated whether polyphenol rich ethyl acetate extract of Aca...

Full description

Bibliographic Details
Main Authors: Tayyaba Afsar, Suhail Razak, Khalid Mujasam Batoo, Muhammad Rashid Khan
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Doxorubicin
Cardiotoxicity
Oxidative stress
Cardiac function biomarkers
Antioxidants
Polyphenolics
Online Access:http://link.springer.com/article/10.1186/s12906-017-2061-0

Internet

http://link.springer.com/article/10.1186/s12906-017-2061-0

Similar Items