Salmonella Typhimurium effector SseI inhibits chemotaxis and increases host cell survival by deamidation of heterotrimeric Gi proteins.

Salmonella enterica serotype Typhimurium (S. Typhimurium) is one of the most frequent causes of food-borne illness in humans and usually associated with acute self-limiting gastroenteritis. However, in immunocompromised patients, the pathogen can disseminate and lead to severe systemic diseases. S....

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Main Authors: Thorsten Brink, Veronika Leiss, Peter Siegert, Doris Jehle, Julia K Ebner, Carsten Schwan, Aliaksei Shymanets, Sebastian Wiese, Bernd Nürnberg, Michael Hensel, Klaus Aktories, Joachim H C Orth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6107295?pdf=render

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